Clinical profile of hypertensive disorders of pregnancy and their association with maternal complications: A cross-sectional observational study.
DOI:
https://doi.org/10.51168/v3y4nw48Keywords:
Eclampsia, Hemolysis, elevated liver enzymes, and low platelet count syndrome, hypertensive disorders of pregnancy, maternal complications, preeclampsia, severe hypertensionAbstract
Background:
Hypertensive disorders of pregnancy are important contributors to maternal morbidity and adverse obstetric outcomes. Early recognition of clinical severity and organ dysfunction is essential for timely management.
Objectives:
To describe the clinical profile of hypertensive disorders of pregnancy and evaluate their association with maternal complications among pregnant women attending a tertiary care hospital.
Methods:
This hospital-based cross-sectional observational study was conducted at Government Medical College/Government General Hospital, Nizamabad, Telangana, India, from April 2025 to September 2025. A total of 100 pregnant women diagnosed with hypertensive disorders of pregnancy were included. Baseline obstetric details, clinical symptoms, blood pressure severity, proteinuria, platelet count, liver enzymes, serum creatinine, and maternal complications were recorded. Associations with maternal complications were assessed using the chi-square test.
Results:
The mean age was 26.8 ± 4.7 years, and 54.0% were multigravidae. Gestational hypertension was observed in 38.0%, preeclampsia without severe features in 22.0%, preeclampsia with severe features in 26.0%, eclampsia in 8.0%, and chronic hypertension with superimposed preeclampsia in 6.0%. Maternal complications occurred in 33.0% of women. Postpartum hemorrhage was the most common complication, followed by placental abruption and HELLP syndrome. Severe hypertensive disorders were significantly associated with maternal complications. Severe-range blood pressure, proteinuria, thrombocytopenia, elevated liver enzymes, and raised serum creatinine were significantly associated with adverse maternal outcomes.
Conclusion:
Severe forms of hypertensive disorders of pregnancy were associated with a higher burden of maternal complications. Clinical severity and biochemical derangements were useful indicators of maternal risk.
Recommendations:
Structured antenatal screening, early referral, and close monitoring of severe features are recommended to reduce maternal morbidity.
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