Benign Neural Tumors: A Cross-Sectional Study of Clinicopathological Characteristics.

Dr Prajna Paramita Samal; Dr Subhashree Shantisudha; Dr Subhashree Subhamita Dash

doi:10.51168/56t52131

Autori

Dr Prajna Paramita Samal Assistant professor Department- Pathology Medical College- IMS and SUM Hospital, Bhubaneswar, Odisha, India
Dr Subhashree Shantisudha Assistant professor Department- Pathology Medical College- IMS and SUM Hospital, Bhubaneswar, Odisha, India
Dr Subhashree Subhamita Dash Assistant professor Department- Pathology Medical College- IMS and SUM Hospital, Bhubaneswar, Odisha, India

DOI:

https://doi.org/10.51168/56t52131

Cuvinte cheie:

Benign neural tumors, Schwannoma, Neurofibroma, Granular cell tumor, Histopathology, Anatomical location

Rezumat

Background

Benign neural tumors comprise a heterogeneous group of neoplasms with diverse clinical and anatomical presentations. This study aimed to evaluate the demographic, histopathological, and anatomical distribution of benign neural tumors and assess the association between tumor type and anatomical location.

Methods

This hospital-based cross-sectional study was conducted at the Department of Pathology, IMS and SUM Hospital, Bhubaneswar, Odisha, India, over a two-year study period. A total of 86 histopathologically confirmed benign neural tumor cases were included. Demographic characteristics, tumor type, and anatomical location were recorded. Histopathological examination was performed using routine hematoxylin and eosin staining. The association between tumor type and anatomical location was assessed using the chi-square test, with p < 0.05 considered statistically significant.

Results

Among 86 cases, the largest proportion was aged 21–40 years (30, 34.9%). Schwannoma was the most common tumor (43, 50.0%), followed by neurofibroma (32, 37.2%) and granular cell tumor (11, 12.8%). The head and neck was the most frequent anatomical site (39, 45.3%), followed by extremities (28, 32.6%), spine (11, 12.8%), and intracranial sites (8, 9.3%). Among granular cell tumors, intracranial location had the highest frequency (4/11, 36.4%), while head and neck and spinal locations each accounted for 3/11 (27.3%). Tumor type was significantly associated with anatomical location (p = 0.04).

Conclusion

Benign neural tumors predominantly affected young to middle-aged individuals, with schwannoma being the most frequent tumor and the head and neck being the most common overall anatomical site. Histopathological evaluation remains essential for accurate diagnosis and classification.

Recommendation

Larger multicentre studies with standardized clinicopathological assessment and longer follow-up are recommended.

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